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The Na(+)/Ca(2+) exchanger NCKX4 governs termination and adaptation of the mammalian olfactory response

Sensory perception requires accurate encoding of stimulus information by sensory receptor cells. Here, we identify NCKX4, a potassium – dependent Na(+)/Ca(2+) exchanger, to be necessary for rapid response termination and proper adaptation of vertebrate olfactory sensory neurons (OSNs). Nckx4(−/−) mo...

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Detalles Bibliográficos
Autores principales: Stephan, Aaron B., Tobochnik, Steven, Dibattista, Michele, Wall, Crystal M., Reisert, Johannes, Zhao, Haiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245797/
https://www.ncbi.nlm.nih.gov/pubmed/22057188
http://dx.doi.org/10.1038/nn.2943