α2 Integrin-Dependent Suppression of Pancreatic Adenocarcinoma Cell Invasion Involves Ectodomain Regulation of Kallikrein-Related Peptidase-5

Previous reports demonstrate that the α2-integrin (α2) mediates pancreatic ductal adenocarcinoma (PDAC) cell interactions with collagens. We found that while well-differentiated cells use α2 exclusively to adhere and migrate on collagenI, poorly differentiated PDAC cells demonstrate reduced reliance...

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Detalles Bibliográficos
Autores principales: Lee, Chia-Yao, Marzan, David, Lin, Grace, Goodison, Steve, Silletti, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245846/
https://www.ncbi.nlm.nih.gov/pubmed/22203845
http://dx.doi.org/10.1155/2011/365651

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245846/
https://www.ncbi.nlm.nih.gov/pubmed/22203845
http://dx.doi.org/10.1155/2011/365651

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