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TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

BACKGROUND AND AIMS: Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an intermediate phenotype linked to genetic susceptibility to CRC. METHODS: In a large sample, the study investigated whether cand...

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Detalles Bibliográficos
Autores principales: Jones, A M, Beggs, A D, Carvajal-Carmona, L, Farrington, S, Tenesa, A, Walker, M, Howarth, K, Ballereau, S, Hodgson, S V, Zauber, A, Bertagnolli, M, Midgley, R, Campbell, H, Kerr, D, Dunlop, M G, Tomlinson, I P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245900/
https://www.ncbi.nlm.nih.gov/pubmed/21708826
http://dx.doi.org/10.1136/gut.2011.239772