DNA damage bypass operates in the S and G2 phases of the cell cycle and exhibits differential mutagenicity

Translesion DNA synthesis (TLS) employs low-fidelity DNA polymerases to bypass replication-blocking lesions, and being associated with chromosomal replication was presumed to occur in the S phase of the cell cycle. Using immunostaining with anti-replication protein A antibodies, we show that in UV-i...

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Detalles Bibliográficos
Autores principales: Diamant, Noam, Hendel, Ayal, Vered, Ilan, Carell, Thomas, Reißner, Thomas, de Wind, Niels, Geacinov, Nicholas, Livneh, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245908/
https://www.ncbi.nlm.nih.gov/pubmed/21908406
http://dx.doi.org/10.1093/nar/gkr596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245908/
https://www.ncbi.nlm.nih.gov/pubmed/21908406
http://dx.doi.org/10.1093/nar/gkr596

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