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The insertion of two 8-methyl-2′-deoxyguanosine residues in tetramolecular quadruplex structures: trying to orientate the strands

In this article, we report a structural study, based on NMR and CD spectroscopies, and molecular modelling of all possible d(TG(3)T) and d(TG(4)T) analogues containing two 8-methyl-2′-deoxyguanosine residues (M). Particularly, the potential ability of these modified residues to orientate the strands...

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Detalles Bibliográficos
Autores principales: Virgilio, Antonella, Esposito, Veronica, Citarella, Giuseppe, Pepe, Antonietta, Mayol, Luciano, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245916/
https://www.ncbi.nlm.nih.gov/pubmed/21908403
http://dx.doi.org/10.1093/nar/gkr670