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mRNA pseudoknot structures can act as ribosomal roadblocks

Several viruses utilize programmed ribosomal frameshifting mediated by mRNA pseudoknots in combination with a slippery sequence to produce a well defined stochiometric ratio of the upstream encoded to the downstream-encoded protein. A correlation between the mechanical strength of mRNA pseudoknots a...

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Detalles Bibliográficos
Autores principales: Tholstrup, Jesper, Oddershede, Lene B., Sørensen, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245918/
https://www.ncbi.nlm.nih.gov/pubmed/21908395
http://dx.doi.org/10.1093/nar/gkr686