Activation and repression functions of an SR splicing regulator depend on exonic versus intronic-binding position

SR proteins and related factors play widespread roles in alternative pre-mRNA splicing and are known to promote splice site recognition through their Arg–Ser-rich effector domains. However, binding of SR regulators to some targets results in repression of splice sites through a distinct mechanism. H...

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Detalles Bibliográficos
Autores principales: Shen, Manli, Mattox, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245930/
https://www.ncbi.nlm.nih.gov/pubmed/21914724
http://dx.doi.org/10.1093/nar/gkr713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245930/
https://www.ncbi.nlm.nih.gov/pubmed/21914724
http://dx.doi.org/10.1093/nar/gkr713

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