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Activation and repression functions of an SR splicing regulator depend on exonic versus intronic-binding position
SR proteins and related factors play widespread roles in alternative pre-mRNA splicing and are known to promote splice site recognition through their Arg–Ser-rich effector domains. However, binding of SR regulators to some targets results in repression of splice sites through a distinct mechanism. H...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245930/ https://www.ncbi.nlm.nih.gov/pubmed/21914724 http://dx.doi.org/10.1093/nar/gkr713 |