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Deep sequencing of virus-infected cells reveals HIV-encoded small RNAs

Small virus-derived interfering RNAs (viRNAs) play an important role in antiviral defence in plants, insects and nematodes by triggering the RNA interference (RNAi) pathway. The role of RNAi as an antiviral defence mechanism in mammalian cells has been obscure due to the lack of viRNA detection. Alt...

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Detalles Bibliográficos
Autores principales: Schopman, Nick C.T., Willemsen, Marcel, Liu, Ying Poi, Bradley, Ted, van Kampen, Antoine, Baas, Frank, Berkhout, Ben, Haasnoot, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245934/
https://www.ncbi.nlm.nih.gov/pubmed/21911362
http://dx.doi.org/10.1093/nar/gkr719