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Transcription factor Sox10 orchestrates activity of a neural crest-specific enhancer in the vicinity of its gene

The Sox10 transcription factor is a central regulator of vertebrate neural crest and nervous system development. Its expression is likely controlled by multiple enhancer elements, among them U3 (alternatively known as MCS4). Here we analyze U3 activity to obtain deeper insights into Sox10 function a...

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Detalles Bibliográficos
Autores principales: Wahlbuhl, Mandy, Reiprich, Simone, Vogl, Michael R., Bösl, Michael R., Wegner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245941/
https://www.ncbi.nlm.nih.gov/pubmed/21908409
http://dx.doi.org/10.1093/nar/gkr734