A cross-sample statistical model for SNP detection in short-read sequencing data

Highly multiplex DNA sequencers have greatly expanded our ability to survey human genomes for previously unknown single nucleotide polymorphisms (SNPs). However, sequencing and mapping errors, though rare, contribute substantially to the number of false discoveries in current SNP callers. We demonst...

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Detalles Bibliográficos
Autores principales: Muralidharan, Omkar, Natsoulis, Georges, Bell, John, Newburger, Daniel, Xu, Hua, Kela, Itai, Ji, Hanlee, Zhang, Nancy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245949/
https://www.ncbi.nlm.nih.gov/pubmed/22064853
http://dx.doi.org/10.1093/nar/gkr851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245949/
https://www.ncbi.nlm.nih.gov/pubmed/22064853
http://dx.doi.org/10.1093/nar/gkr851

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