Increased in vivo inhibition of gene expression by combining RNA interference and U1 inhibition

Inhibition of gene expression can be achieved with RNA interference (RNAi) or U1 small nuclear RNA—snRNA—interference (U1i). U1i is based on U1 inhibitors (U1in), U1 snRNA molecules modified to inhibit polyadenylation of a target pre-mRNA. In culture, we have shown that the combination of RNAi and U...

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Detalles Bibliográficos
Autores principales: Blazquez, Lorea, Gonzalez-Rojas, Sandra Jovanna, Abad, Amaya, Razquin, Nerea, Abad, Xabier, Fortes, Puri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245954/
https://www.ncbi.nlm.nih.gov/pubmed/22086952
http://dx.doi.org/10.1093/nar/gkr956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245954/
https://www.ncbi.nlm.nih.gov/pubmed/22086952
http://dx.doi.org/10.1093/nar/gkr956

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