Gab Adapter Proteins as Therapeutic Targets for Hematologic Disease

The Grb-2 associated binder (Gab) family of scaffolding/adaptor/docking proteins is a group of three molecules with significant roles in cytokine receptor signaling. Gabs possess structural motifs for phosphorylation-dependent receptor recruitment, Grb2 binding, and activation of downstream signalin...

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Detalles Bibliográficos
Autores principales: Verma, Sheetal, Vaughan, Tamisha, Bunting, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246295/
https://www.ncbi.nlm.nih.gov/pubmed/22216034
http://dx.doi.org/10.1155/2012/380635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246295/
https://www.ncbi.nlm.nih.gov/pubmed/22216034
http://dx.doi.org/10.1155/2012/380635

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