Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

Time and resource constraints necessitate increasingly early decisions to advance or halt pre-clinical drug discovery programs. Early discovery or “tool” compounds may be potent inhibitors of new targets, but all too often they exhibit poor pharmaceutical and pharmacokinetic properties that make ear...

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Detalles Bibliográficos
Autores principales: Wahlstrom, Jan L, Chiang, Po-Chang, Ghosh, Sarbani, Warren, Chad J, Wene, Steve P, Albin, Lesley A, Smith, Mark E, Roberds, Steven L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2007
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246351/
http://dx.doi.org/10.1007/s11671-007-9063-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246351/
http://dx.doi.org/10.1007/s11671-007-9063-7

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