Hypoxia-Induced Invadopodia Formation Involves Activation of NHE-1 by the p90 Ribosomal S6 Kinase (p90RSK)

The hypoxic and acidic microenvironments in tumors are strongly associated with malignant progression and metastasis, and have thus become a central issue in tumor physiology and cancer treatment. Despite this, the molecular links between acidic pH- and hypoxia-mediated cell invasion/metastasis rema...

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Detalles Bibliográficos
Autores principales: Lucien, Fabrice, Brochu-Gaudreau, Karine, Arsenault, Dominique, Harper, Kelly, Dubois, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246449/
https://www.ncbi.nlm.nih.gov/pubmed/22216126
http://dx.doi.org/10.1371/journal.pone.0028851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246449/
https://www.ncbi.nlm.nih.gov/pubmed/22216126
http://dx.doi.org/10.1371/journal.pone.0028851

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