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Loops Determine the Mechanical Properties of Mitotic Chromosomes
We introduce a new polymer model for mitotic chromosomes. The key assumption of the model is the ability of the chromatin fibre to cross-link to itself due to binding proteins. These protein-chromatin interactions are included by a probabilistic and dynamic mechanism. The hypothesis is motivated by...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246460/ https://www.ncbi.nlm.nih.gov/pubmed/22216220 http://dx.doi.org/10.1371/journal.pone.0029225 |