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Biased Use of the IGHV4 Family and Evidence for Antigen Selection in Chlamydophila psittaci-Negative Ocular Adnexal Extranodal Marginal Zone Lymphomas

Extranodal marginal zone lymphomas (EMZL) are the most common lymphomas in the ocular adnexa. The etiology and potential role for antigenic stimulation in these lymphomas are still controversial. We have examined IGHV gene usage and mutations in 67 Chlamydophila psittaci-negative ocular adnexal EMZL...

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Detalles Bibliográficos
Autores principales: Zhu, Daxing, Lossos, Chen, Chapman-Fredricks, Jennifer R., Matthews, Julie M., Ikpatt, Offiong F., Ruiz, Phillip, Lossos, Izidore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246466/
https://www.ncbi.nlm.nih.gov/pubmed/22216179
http://dx.doi.org/10.1371/journal.pone.0029114