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Chronic Deficiency of Nitric Oxide Affects Hypoxia Inducible Factor-1α (HIF-1α) Stability and Migration in Human Endothelial Cells

BACKGROUND: Endothelial dysfunction in widely diffuse disorders, such as atherosclerosis, hypertension, diabetes and senescence, is associated with nitric oxide (NO) deficiency. Here, the behavioural and molecular consequences deriving from NO deficiency in human umbilical vein endothelial cells (HU...

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Detalles Bibliográficos
Autores principales: Cattaneo, Maria Grazia, Cappellini, Elisa, Benfante, Roberta, Ragni, Maurizio, Omodeo-Salè, Fausta, Nisoli, Enzo, Borgese, Nica, Vicentini, Lucia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246476/
https://www.ncbi.nlm.nih.gov/pubmed/22216344
http://dx.doi.org/10.1371/journal.pone.0029680