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The HIV-1 Transactivator Factor (Tat) Induces Enterocyte Apoptosis through a Redox-Mediated Mechanism

The intestinal mucosa is an important target of human immunodeficiency virus (HIV) infection. HIV virus induces CD4+ T cell loss and epithelial damage which results in increased intestinal permeability. The mechanisms involved in nutrient malabsorption and alterations of intestinal mucosal architect...

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Detalles Bibliográficos
Autores principales: Buccigrossi, Vittoria, Laudiero, Gabriella, Nicastro, Emanuele, Miele, Erasmo, Esposito, Franca, Guarino, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246489/
https://www.ncbi.nlm.nih.gov/pubmed/22216281
http://dx.doi.org/10.1371/journal.pone.0029436