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Granulysin-Expressing CD4(+) T Cells as Candidate Immune Marker for Tuberculosis during Childhood and Adolescence

BACKGROUND: Granulysin produced by cytolytic T cells directly contributes to immune defense against tuberculosis (TB). We investigated granulysin as a candidate immune marker for childhood and adolescent TB. METHODS: Peripheral blood mononuclear cells (PBMC) from children and adolescents (1–17 years...

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Detalles Bibliográficos
Autores principales: Mueller, Henrik, Faé, Kellen C., Magdorf, Klaus, Ganoza, Christian A., Wahn, Ulrich, Guhlich, Ute, Feiterna-Sperling, Cornelia, Kaufmann, Stefan H. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246496/
https://www.ncbi.nlm.nih.gov/pubmed/22216262
http://dx.doi.org/10.1371/journal.pone.0029367