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Translational Regulation of Utrophin by miRNAs

BACKGROUND: Utrophin is the autosomal homolog of dystrophin, the product of the Duchenne Muscular Dystrophy (DMD) locus. Its regulation is of therapeutic interest as its overexpression can compensate for dystrophin's absence in animal models of DMD. The tissue distribution and transcriptional r...

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Detalles Bibliográficos
Autores principales: Basu, Utpal, Lozynska, Olga, Moorwood, Catherine, Patel, Gopal, Wilton, Steve D., Khurana, Tejvir S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246502/
https://www.ncbi.nlm.nih.gov/pubmed/22216264
http://dx.doi.org/10.1371/journal.pone.0029376