Cargando…

Whole-genome sequencing of rifampicin-resistant M. tuberculosis strains identifies compensatory mutations in RNA polymerase

Drug-resistant bacteria are emerging worldwide, despite frequently being less fit than drug-susceptible strains(1). Data from model systems suggest the fitness cost of antimicrobial resistance can be mitigated by compensatory mutations(2). However, current evidence that compensatory evolution plays...

Descripción completa

Detalles Bibliográficos
Autores principales:	Comas, Iñaki, Borrell, Sonia, Roetzer, Andreas, Rose, Graham, Malla, Bijaya, Kato-Maeda, Midori, Galagan, James, Niemann, Stefan, Gagneux, Sebastien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246538/ https://www.ncbi.nlm.nih.gov/pubmed/22179134 http://dx.doi.org/10.1038/ng.1038

Ejemplares similares

Two New Rapid SNP-Typing Methods for Classifying Mycobacterium tuberculosis Complex into the Main Phylogenetic Lineages
por: Stucki, David, et al.
Publicado: (2012)

Out-of-Africa migration and Neolithic co-expansion of Mycobacterium tuberculosis with modern humans
por: Comas, Iñaki, et al.
Publicado: (2013)

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved
por: Comas, Iñaki, et al.
Publicado: (2010)

Effect of compensatory evolution in the emergence and transmission of rifampicin-resistant Mycobacterium tuberculosis in Cape Town, South Africa: a genomic epidemiology study
por: Goig, Galo A, et al.
Publicado: (2023)

Genotyping of Genetically Monomorphic Bacteria: DNA Sequencing in Mycobacterium tuberculosis Highlights the Limitations of Current Methodologies
por: Comas, Iñaki, et al.
Publicado: (2009)

First Insights into the Phylogenetic Diversity of Mycobacterium tuberculosis in Nepal
por: Malla, Bijaya, et al.
Publicado: (2012)

Compensatory evolution drives multidrug-resistant tuberculosis in Central Asia
por: Merker, Matthias, et al.
Publicado: (2018)

The Past and Future of Tuberculosis Research
por: Comas, Iñaki, et al.
Publicado: (2009)

Evaluation of Customised Lineage-Specific Sets of MIRU-VNTR Loci for Genotyping Mycobacterium tuberculosis Complex Isolates in Ghana
por: Asante-Poku, Adwoa, et al.
Publicado: (2014)

Enriched whole genome sequencing identified compensatory mutations in the RNA polymerase gene of rifampicin-resistant Mycobacterium leprae strains
por: Lavania, Mallika, et al.
Publicado: (2018)

“Pseudo-Beijing”: Evidence for Convergent Evolution in the Direct Repeat Region of Mycobacterium tuberculosis
por: Fenner, Lukas, et al.
Publicado: (2011)

Mapping of Genotype–Phenotype Diversity among Clinical Isolates of Mycobacterium tuberculosis by Sequence-Based Transcriptional Profiling
por: Rose, Graham, et al.
Publicado: (2013)

Genetic diversity within Mycobacterium tuberculosis complex impacts on the accuracy of genotypic pyrazinamide drug-susceptibility assay
por: Köser, Claudio U., et al.
Publicado: (2014)

Whole-Genome Sequencing Has the Potential To Improve Treatment for Rifampicin-Resistant Tuberculosis in High-Burden Settings: a Retrospective Cohort Study
por: Cox, Helen, et al.
Publicado: (2022)

Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development
por: Borrell, Sònia, et al.
Publicado: (2019)

Rifampicin Resistance: Fitness Costs and the Significance of Compensatory Evolution
por: Hughes, Diarmaid, et al.
Publicado: (2013)

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages
por: Portevin, Damien, et al.
Publicado: (2011)

Use of Whole Genome Sequencing to Determine the Microevolution of Mycobacterium tuberculosis during an Outbreak
por: Kato-Maeda, Midori, et al.
Publicado: (2013)

Rifampicin-Monoresistant Tuberculosis Is Not the Same as Multidrug-Resistant Tuberculosis: a Descriptive Study from Khayelitsha, South Africa
por: Salaam-Dreyer, Zubeida, et al.
Publicado: (2021)

Comment on: Characterization of the embB gene in Mycobacterium tuberculosis isolates from Barcelona and rapid detection of main mutations related to ethambutol resistance using a low-density DNA array
por: Köser, Claudio U., et al.
Publicado: (2014)

The within-host evolution of antimicrobial resistance in Mycobacterium tuberculosis
por: Castro, Rhastin A D, et al.
Publicado: (2020)

The Troika Host–Pathogen–Extrinsic Factors in Tuberculosis: Modulating Inflammation and Clinical Outcomes
por: Bastos, Helder Novais, et al.
Publicado: (2018)

Evolution of Drug Resistance in Tuberculosis: Recent Progress and Implications for Diagnosis and Therapy
por: Trauner, Andrej, et al.
Publicado: (2014)

Compensatory effects of M. tuberculosis rpoB mutations outside the rifampicin resistance-determining region
por: Ma, Pengjiao, et al.
Publicado: (2021)

HIV Coinfection Is Associated with Low-Fitness rpoB Variants in Rifampicin-Resistant Mycobacterium tuberculosis
por: Loiseau, Chloé, et al.
Publicado: (2020)

Transcriptional Approach for Decoding the Mechanism of rpoC Compensatory Mutations for the Fitness Cost in Rifampicin-Resistant Mycobacterium tuberculosis
por: Xu, Zhihong, et al.
Publicado: (2018)

Potential contribution of HIV during first-line tuberculosis treatment to subsequent rifampicin-monoresistant tuberculosis and acquired tuberculosis drug resistance in South Africa: a retrospective molecular epidemiology study
por: Cox, Helen, et al.
Publicado: (2021)

Drug resistance-conferring mutations in Mycobacterium tuberculosis from Madang, Papua New Guinea
por: Ballif, Marie, et al.
Publicado: (2012)

KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes
por: Steiner, Andreas, et al.
Publicado: (2014)

Developing customized stepwise MIRU-VNTR typing for tuberculosis surveillance in Georgia
por: Maghradze, Nino, et al.
Publicado: (2022)

Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing
por: Maghradze, Nino, et al.
Publicado: (2019)

Could high-concentration rifampicin kill rifampicin-resistant M. tuberculosis? Rifampicin MIC test in rifampicin-resistant isolates from patients with osteoarticular tuberculosis
por: Zhang, Zehua, et al.
Publicado: (2014)

Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee
por: Coscolla, Mireia, et al.
Publicado: (2013)

Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin
por: Hamouche, Lina, et al.
Publicado: (2021)

Whole-Genome Sequencing for Drug Resistance Profile Prediction in Mycobacterium tuberculosis
por: Gygli, Sebastian M., et al.
Publicado: (2019)

Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants
por: Monama, Mokgerwa Zacharia, et al.
Publicado: (2023)

Local adaptation in populations of Mycobacterium tuberculosis endemic to the Indian Ocean Rim
por: Menardo, Fabrizio, et al.
Publicado: (2021)

Whole Genome Sequencing and Spatial Analysis Identifies Recent Tuberculosis Transmission Hotspots in Ghana
por: Asare, Prince, et al.
Publicado: (2020)

Airway microecology in rifampicin-resistant and rifampicin-sensitive pulmonary tuberculosis patients
por: Cai, Xingshan, et al.
Publicado: (2022)

Transition bias influences the evolution of antibiotic resistance in Mycobacterium tuberculosis
por: Payne, Joshua L., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_leebol15aapbhdq7g0d6qouecr