Large-Scale Discovery of Enhancers from Human Heart Tissue

Development and function of the human heart depend on the dynamic control of tissue-specific gene expression by distant-acting transcriptional enhancers. To generate an accurate genome-wide map of human heart enhancers, we used an epigenomic enhancer discovery approach and identified ∼6,200 candidat...

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Detalles Bibliográficos
Autores principales: May, Dalit, Blow, Matthew J., Kaplan, Tommy, McCulley, David J., Jensen, Brian C., Akiyama, Jennifer A., Holt, Amy, Plajzer-Frick, Ingrid, Shoukry, Malak, Wright, Crystal, Afzal, Veena, Simpson, Paul C., Rubin, Edward M., Black, Brian L., Bristow, James, Pennacchio, Len A., Visel, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246570/
https://www.ncbi.nlm.nih.gov/pubmed/22138689
http://dx.doi.org/10.1038/ng.1006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246570/
https://www.ncbi.nlm.nih.gov/pubmed/22138689
http://dx.doi.org/10.1038/ng.1006

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