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ER Stress and Apoptosis: A New Mechanism for Retinal Cell Death

The endoplasmic reticulum (ER) is the primary subcellular organelle where proteins are synthesized and folded. When the homeostasis of the ER is disturbed, unfolded or misfolded proteins accumulate in the ER lumen, resulting in ER stress. In response to ER stress, cells activate a set of tightly con...

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Detalles Bibliográficos
Autores principales: Jing, Guangjun, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246718/
https://www.ncbi.nlm.nih.gov/pubmed/22216020
http://dx.doi.org/10.1155/2012/589589