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Rosiglitazone and Pioglitazone Alter Aromatase Kinetic Properties in Human Granulosa Cells
We have previously reported that, in human granulosa cells, thiazolidinediones rosiglitazone and pioglitazone inhibit estrogen synthesis by interfering with androgen binding to aromatase, without an effect on aromatase mRNA or protein expression. In the current paper, we explore the effects of rosig...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246782/ https://www.ncbi.nlm.nih.gov/pubmed/22220166 http://dx.doi.org/10.1155/2011/926438 |