Cargando…

Rosiglitazone and Pioglitazone Alter Aromatase Kinetic Properties in Human Granulosa Cells

We have previously reported that, in human granulosa cells, thiazolidinediones rosiglitazone and pioglitazone inhibit estrogen synthesis by interfering with androgen binding to aromatase, without an effect on aromatase mRNA or protein expression. In the current paper, we explore the effects of rosig...

Descripción completa

Detalles Bibliográficos
Autores principales: Araki, Takako, Varadinova, Miroslava, Goldman, Michael, Rosenwaks, Zev, Poretsky, Leonid, Seto-Young, Donna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246782/
https://www.ncbi.nlm.nih.gov/pubmed/22220166
http://dx.doi.org/10.1155/2011/926438