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PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis
The microtubule-organizing activity of the centrosome oscillates during the cell cycle, reaching its highest level at mitosis. At the onset of mitosis, the centrosome undergoes maturation, which is characterized by a drastic expansion of the pericentriolar matrix (PCM) and a robust increase in micro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246884/ https://www.ncbi.nlm.nih.gov/pubmed/22184200 http://dx.doi.org/10.1083/jcb.201106093 |