Aurora A and Aurora B jointly coordinate chromosome segregation and anaphase microtubule dynamics

We established a conditional deletion of Aurora A kinase (AurA) in Cdk1 analogue-sensitive DT40 cells to analyze AurA knockout phenotypes after Cdk1 activation. In the absence of AurA, cells form bipolar spindles but fail to properly align their chromosomes and exit mitosis with segregation errors....

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Detalles Bibliográficos
Autores principales: Hégarat, Nadia, Smith, Ewan, Nayak, Gowri, Takeda, Shunichi, Eyers, Patrick A., Hochegger, Helfrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246887/
https://www.ncbi.nlm.nih.gov/pubmed/22184196
http://dx.doi.org/10.1083/jcb.201105058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246887/
https://www.ncbi.nlm.nih.gov/pubmed/22184196
http://dx.doi.org/10.1083/jcb.201105058

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