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Smaug1 mRNA-silencing foci respond to NMDA and modulate synapse formation

Mammalian Smaug1/Samd4A is a translational repressor. Here we show that Smaug1 forms mRNA-silencing foci located at postsynapses of hippocampal neurons. These structures, which we have named S-foci, are distinct from P-bodies, stress granules, or other neuronal RNA granules hitherto described, and a...

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Detalles Bibliográficos
Autores principales: Baez, María Verónica, Luchelli, Luciana, Maschi, Darío, Habif, Martín, Pascual, Malena, Thomas, María Gabriela, Boccaccio, Graciela Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246892/
https://www.ncbi.nlm.nih.gov/pubmed/22201125
http://dx.doi.org/10.1083/jcb.201108159