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A new method for identifying bivariate differential expression in high dimensional microarray data using quadratic discriminant analysis

BACKGROUND: One of the drawbacks we face up when analyzing gene to phenotype associations in genomic data is the ugly performance of the designed classifier due to the small sample-high dimensional data structures (n ≪ p) at hand. This is known as the peaking phenomenon, a common situation in the an...

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Detalles Bibliográficos
Autores principales: Arevalillo, Jorge M, Navarro, Hilario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247087/
https://www.ncbi.nlm.nih.gov/pubmed/22168481
http://dx.doi.org/10.1186/1471-2105-12-S12-S6