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A robust penalized method for the analysis of noisy DNA copy number data

BACKGROUND: Deletions and amplifications of the human genomic DNA copy number are the causes of numerous diseases, such as, various forms of cancer. Therefore, the detection of DNA copy number variations (CNV) is important in understanding the genetic basis of many diseases. Various techniques and p...

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Detalles Bibliográficos
Autores principales: Gao, Xiaoli, Huang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247090/
https://www.ncbi.nlm.nih.gov/pubmed/20868505
http://dx.doi.org/10.1186/1471-2164-11-517