The Effect of a High-Fat Breakfast on the Pharmacokinetics of Moxidectin in Healthy Male Subjects: A Randomized Phase I Trial

The objective of this study was to assess the effect of a high-fat meal on the pharmacokinetics of moxidectin. Healthy male subjects were randomized to receive single oral 8 mg doses of moxidectin after an overnight fast or high-fat breakfast. In fasted subjects (N = 27), mean [SD] parameters were C...

Descripción completa

Detalles Bibliográficos
Autores principales: Korth-Bradley, Joan M., Parks, Virginia, Chalon, Stephan, Gourley, Ian, Matschke, Kyle, Cailleux, Karine, Fitoussi, Serge, Fleckenstein, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247120/
https://www.ncbi.nlm.nih.gov/pubmed/22232462
http://dx.doi.org/10.4269/ajtmh.2012.11-0415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247120/
https://www.ncbi.nlm.nih.gov/pubmed/22232462
http://dx.doi.org/10.4269/ajtmh.2012.11-0415

Ejemplares similares