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An improved classification of G-protein-coupled receptors using sequence-derived features

BACKGROUND: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures of GPCRs are largely unavailable; however, a large number of GPCR primary sequences are known. To facilitate the ident...

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Detalles Bibliográficos
Autores principales: Peng, Zhen-Ling, Yang, Jian-Yi, Chen, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247138/
https://www.ncbi.nlm.nih.gov/pubmed/20696050
http://dx.doi.org/10.1186/1471-2105-11-420