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An improved classification of G-protein-coupled receptors using sequence-derived features
BACKGROUND: G-protein-coupled receptors (GPCRs) play a key role in diverse physiological processes and are the targets of almost two-thirds of the marketed drugs. The 3 D structures of GPCRs are largely unavailable; however, a large number of GPCR primary sequences are known. To facilitate the ident...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247138/ https://www.ncbi.nlm.nih.gov/pubmed/20696050 http://dx.doi.org/10.1186/1471-2105-11-420 |