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Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β
BACKGROUND: Amyloid β (Aβ) accumulates in Alzheimer's disease (AD) brain. Microglial activation also occurs in AD, and this inflammatory response may contribute to disease progression. Microglial activation can be induced by Aβ, but the mechanisms by which this occurs have not been defined. The...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247192/ https://www.ncbi.nlm.nih.gov/pubmed/22051244 http://dx.doi.org/10.1186/1742-2094-8-152 |