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Zebrafish prox1b Mutants Develop a Lymphatic Vasculature, and prox1b Does Not Specifically Mark Lymphatic Endothelial Cells

BACKGROUND: The expression of the Prospero homeodomain transcription factor (Prox1) in a subset of cardinal venous cells specifies the lymphatic lineage in mice. Prox1 is also indispensible for the maintenance of lymphatic cell fate, and is therefore considered a master control gene for lymphangioge...

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Detalles Bibliográficos
Autores principales: Tao, Shijie, Witte, Merlijn, Bryson-Richardson, Robert J., Currie, Peter D., Hogan, Benjamin M., Schulte-Merker, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247213/
https://www.ncbi.nlm.nih.gov/pubmed/22216143
http://dx.doi.org/10.1371/journal.pone.0028934