Pax3 Stimulates p53 Ubiquitination and Degradation Independent of Transcription

BACKGROUND: Pax3 is a developmental transcription factor that is required for neural tube and neural crest development. We previously showed that inactivating the p53 tumor suppressor protein prevents neural tube and cardiac neural crest defects in Pax3-mutant mouse embryos. This demonstrates that P...

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Detalles Bibliográficos
Autores principales: Wang, Xiao Dan, Morgan, Sarah C., Loeken, Mary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247257/
https://www.ncbi.nlm.nih.gov/pubmed/22216266
http://dx.doi.org/10.1371/journal.pone.0029379

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247257/
https://www.ncbi.nlm.nih.gov/pubmed/22216266
http://dx.doi.org/10.1371/journal.pone.0029379

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