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Domain Analysis Reveals That a Deubiquitinating Enzyme USP13 Performs Non-Activating Catalysis for Lys63-Linked Polyubiquitin

Deubiquitination is a reverse process of cellular ubiquitination important for many biological events. Ubiquitin (Ub)-specific protease 13 (USP13) is an ortholog of USP5 implicated in catalyzing hydrolysis of various Ub chains, but its enzymatic properties and catalytic regulation remain to be explo...

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Detalles Bibliográficos
Autores principales: Zhang, Yu-Hang, Zhou, Chen-Jie, Zhou, Zi-Ren, Song, Ai-Xin, Hu, Hong-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247260/
https://www.ncbi.nlm.nih.gov/pubmed/22216260
http://dx.doi.org/10.1371/journal.pone.0029362