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Molecular Insights into the Pathogenesis of Alzheimer's Disease and Its Relationship to Normal Aging

Alzheimer's disease (AD) is a complex neurodegenerative disorder that diverges from the process of normal brain aging by unknown mechanisms. We analyzed the global structure of age- and disease-dependent gene expression patterns in three regions from more than 600 brains. Gene expression variat...

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Detalles Bibliográficos
Autores principales: Podtelezhnikov, Alexei A., Tanis, Keith Q., Nebozhyn, Michael, Ray, William J., Stone, David J., Loboda, Andrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247273/
https://www.ncbi.nlm.nih.gov/pubmed/22216330
http://dx.doi.org/10.1371/journal.pone.0029610