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Profiling Insulin Like Factor 3 (INSL3) Signaling in Human Osteoblasts
BACKGROUND: Young men with mutations in the gene for the INSL3 receptor (Relaxin family peptide 2, RXFP2) are at risk of reduced bone mass and osteoporosis. Consistent with the human phenotype, bone analyses of Rxfp2 (−/−) mice showed decreased bone volume, alterations of the trabecular bone, reduce...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247287/ https://www.ncbi.nlm.nih.gov/pubmed/22216350 http://dx.doi.org/10.1371/journal.pone.0029733 |