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Profiling Insulin Like Factor 3 (INSL3) Signaling in Human Osteoblasts

BACKGROUND: Young men with mutations in the gene for the INSL3 receptor (Relaxin family peptide 2, RXFP2) are at risk of reduced bone mass and osteoporosis. Consistent with the human phenotype, bone analyses of Rxfp2 (−/−) mice showed decreased bone volume, alterations of the trabecular bone, reduce...

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Detalles Bibliográficos
Autores principales: Ferlin, Alberto, Perilli, Lisa, Gianesello, Lisa, Taglialavoro, Giuseppe, Foresta, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247287/
https://www.ncbi.nlm.nih.gov/pubmed/22216350
http://dx.doi.org/10.1371/journal.pone.0029733