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Paliperidone: 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]eth­yl}-9-hy­droxy-2-methyl-1,6,7,8,9,9a-hexa­hydro­pyrido[1,2-a]pyrimidin-4-one

The title compound (also known as 9-hy­droxy­risperidone), C(23)H(27)FN(4)O(3), is a heterocyclic compound with manifold pharmacological properties. The hy­droxy group shows disorder over two positions, with site-occupancy factors of 0.856 (2) and 0.144 (2). The piperidine ring adopts a chair confor...

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Detalles Bibliográficos
Autores principales: Betz, Richard, Gerber, Thomas, Hosten, Eric, Dayananda, Alaloor S., Yathirajan, Hemmige S., Thomas, Saji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247356/
https://www.ncbi.nlm.nih.gov/pubmed/22219974
http://dx.doi.org/10.1107/S160053681104164X