Ascorbate and thiol antioxidants abolish sensitivity of yeast Saccharomyces cerevisiae to disulfiram

Sensitivity of baker’s yeast to disulfiram (DSF) and hypersensitivity of a mutant devoid of Cu, Zn-superoxide dismutase to this compound is reported, demonstrating that yeast may be a simple convenient eukaryotic model to study the mechanism of DSF toxicity. DSF was found to induce oxidative stress...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwolek-Mirek, Magdalena, Zadrag-Tecza, Renata, Bartosz, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247666/
https://www.ncbi.nlm.nih.gov/pubmed/21866320
http://dx.doi.org/10.1007/s10565-011-9200-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247666/
https://www.ncbi.nlm.nih.gov/pubmed/21866320
http://dx.doi.org/10.1007/s10565-011-9200-z

Ejemplares similares