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Purifying Selection Can Obscure the Ancient Age of Viral Lineages

Statistical methods for molecular dating of viral origins have been used extensively to infer the time of most common recent ancestor for many rapidly evolving pathogens. However, there are a number of cases, in which epidemiological, historical, or genomic evidence suggests much older viral origins...

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Detalles Bibliográficos
Autores principales: Wertheim, Joel O., Kosakovsky Pond, Sergei L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247791/
https://www.ncbi.nlm.nih.gov/pubmed/21705379
http://dx.doi.org/10.1093/molbev/msr170