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Activin enhances skin tumourigenesis and malignant progression by inducing a pro-tumourigenic immune cell response

Activin is an important orchestrator of wound repair, but its potential role in skin carcinogenesis has not been addressed. Here we show using different types of genetically modified mice that enhanced levels of activin in the skin promote skin tumour formation and their malignant progression throug...

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Detalles Bibliográficos
Autores principales: Antsiferova, Maria, Huber, Marcel, Meyer, Michael, Piwko-Czuchra, Aleksandra, Ramadan, Tamara, MacLeod, Amanda S., Havran, Wendy L., Dummer, Reinhard, Hohl, Daniel, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247817/
https://www.ncbi.nlm.nih.gov/pubmed/22146395
http://dx.doi.org/10.1038/ncomms1585