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Incorporation of covariates in simultaneous localization of two linked loci using affected relative pairs

BACKGROUND: Many dichotomous traits for complex diseases are often involved more than one locus and/or associated with quantitative biomarkers or environmental factors. Incorporating these quantitative variables into linkage analysis as well as localizing two linked disease loci simultaneously could...

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Detalles Bibliográficos
Autores principales: Chiu, Yen-Feng, Chiou, Jeng-Min, Liang, Kung-Yee, Lee, Chun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247820/
https://www.ncbi.nlm.nih.gov/pubmed/20626914
http://dx.doi.org/10.1186/1471-2156-11-67