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Tazarotene-induced gene 1 inhibits prostaglandin E2-stimulated HCT116 colon cancer cell growth

BACKGROUND: The tazarotene-induced gene 1 (TIG1) is a putative tumor suppressor gene. We have recently demonstrated both TIG1A and TIG1B isoforms inhibited cell growth and induced the expression of G protein-coupled receptor kinase 5 (GRK5) in colon cancer cells. Because elevated prostaglandin E2 (P...

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Detalles Bibliográficos
Autores principales: Tsai, Fu-Ming, Wu, Chang-Chieh, Shyu, Rong-Yaun, Wang, Chun-Hua, Jiang, Shun-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247857/
https://www.ncbi.nlm.nih.gov/pubmed/22126303
http://dx.doi.org/10.1186/1423-0127-18-88