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Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin

BACKGROUND: Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, lipid levels and lipid-lowering response to statins. We evaluated the effects on APOE expression of hypercholesterolemia, APOE ε2/ε3...

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Detalles Bibliográficos
Autores principales: Cerda, Alvaro, Genvigir, Fabiana DV, Willrich, Maria AV, Arazi, Simone S, Bernik, Marcia MS, Dorea, Egidio L, Bertolami, Marcelo C, Faludi, Andre A, Hirata, Mario H, Hirata, Rosario DC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247903/
https://www.ncbi.nlm.nih.gov/pubmed/22074026
http://dx.doi.org/10.1186/1476-511X-10-206