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Correlated mutations via regularized multinomial regression

BACKGROUND: In addition to sequence conservation, protein multiple sequence alignments contain evolutionary signal in the form of correlated variation among amino acid positions. This signal indicates positions in the sequence that influence each other, and can be applied for the prediction of intra...

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Detalles Bibliográficos
Autores principales: Sreekumar, Janardanan, ter Braak, Cajo JF, van Ham, Roeland CHJ, van Dijk, Aalt DJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247924/
https://www.ncbi.nlm.nih.gov/pubmed/22082126
http://dx.doi.org/10.1186/1471-2105-12-444