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Correlated mutations via regularized multinomial regression
BACKGROUND: In addition to sequence conservation, protein multiple sequence alignments contain evolutionary signal in the form of correlated variation among amino acid positions. This signal indicates positions in the sequence that influence each other, and can be applied for the prediction of intra...
Autores principales: | Sreekumar, Janardanan, ter Braak, Cajo JF, van Ham, Roeland CHJ, van Dijk, Aalt DJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247924/ https://www.ncbi.nlm.nih.gov/pubmed/22082126 http://dx.doi.org/10.1186/1471-2105-12-444 |
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