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The anti-apoptotic members of the Bcl-2 family are attractive tumor-associated antigens

Anti-apoptotic members of the Bcl-2 family (Bcl-2, Bcl-X(L) and Mcl-2) are pivotal regulators of apoptotic cell death. They are all highly overexpressed in cancers of different origin in which they enhance the survival of the cancer cells. Consequently, they represent prime candidates for anti-cance...

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Detalles Bibliográficos
Autores principales: thor Straten, Per, Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248102/
https://www.ncbi.nlm.nih.gov/pubmed/21304176